DrugRepV_1615 | Quinacrine Hydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Investigational | 26834994 |
DrugRepV_1616 | Pyronaridine tetraphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_1617 | Tilorone Dihydrochloride | NA | Viral infections | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | NA | 26834994 |
DrugRepV_1618 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_5491 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5492 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5493 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5494 | Artesunate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5495 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5496 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5497 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5498 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5499 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5500 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5501 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_5502 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_6196 | (2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-acetamido-5-[(prop-1-en-2-yl)amino]pentanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]hexanamido]-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.31 ± 0.06 Log PFU/ml) | NA | 25823617 |
DrugRepV_6197 | (E)-N-[(E)-({4-[(E)-{[(diaminomethylidene)amino]imino}methyl]phenyl}methylidene)amino]ethanimidamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.37 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6198 | (2S)-6-amino-N-[(1S)-4-carbamimidamido-1-[(5-carbamimidamido-1-oxopentan-2-yl)carbamoyl]butyl]-2-[(2S)-2-(phenylformamido)propanamido]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.38 ± 0.10 Log PFU/ml) | NA | 25823617 |
DrugRepV_6199 | 7-[(phenylamino)(pyridin-2-yl)methyl]quinolin-8-ol | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.34 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6200 | 1,8-dihydroxy-4,5-dinitro-9,10-dihydroanthracene-9,10-dione | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (50 %) | NA | 25823617 |
DrugRepV_6201 | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.30 ± 0.10 Log PFU/ml) | NA | 25823617 |
DrugRepV_6202 | 4-nitrophenyl 4-carbamimidamidobenzoate | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.41 ± 0.17 Log PFU/ml) | NA | 25823617 |
DrugRepV_6203 | (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.46 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6204 | 4-[2-(2,4-dinitrophenyl)diazen-1-yl]naphthalen-1-ol | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.49 ± 0.26 Log PFU/ml) | NA | 25823617 |
DrugRepV_6205 | 1-ethyl-2-[(1E)-3-[(2Z)-1-ethyl-1H,2H-naphtho[1,2-d][1,3]oxazol-2-ylidene]prop-1-en-1-yl]naphtho[1,2-d][1,3]oxazol-1-ium | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (50 %) | NA | 25823617 |
DrugRepV_6206 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-(phenylformamido)pentanamido]-N-[(1R)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.35 ± 0.21 Log PFU/ml) | NA | 25823617 |
DrugRepV_6207 | (4R,7S,10S,13S,16S,22R)-22-amino-10,16-bis(4-aminobutyl)-13-(3-carbamimidamidopropyl)-7-(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.46 ± 0.35 Log PFU/ml) | NA | 25823617 |
DrugRepV_6208 | 1-[N-(2-ethylhexyl)carbamimidamido]-N-(6-{N-[N-(2-ethylhexyl)carbamimidoyl]carbamimidamido}hexyl)methanimidamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.62 ± 0.20 Log PFU/ml) | NA | 25823617 |
DrugRepV_6209 | (1R,2R,4S,5S,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6-[(2S)-butan-2-yl]-21,24-dihydroxy-12-{[(2R,4S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11,13,22-tetramethyl-3,7,19-trioxaspiro[oxane-2,6-tet | NA | NA | Dengue virus | NA | | Cell based assay | Decrease | NA | 25823617 |
DrugRepV_6210 | (1R,2R,4S,5S,6S,8R,10E,13S,14E,16E,20R,21E,24S)-6-cyclohexyl-24-hydroxy-12-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-21-(hydroxyimino)-5,11,13,22-tetramethyl-3,7,19-trioxaspiro[oxane-2,6-tetracyclo[15.6.1.14,8.0 | NA | NA | Dengue virus | NA | | Cell based assay | Decrease | NA | 25823617 |
DrugRepV_7791 | Ferruginol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cell based assay | Decrease (50 %) | NA | 17663539 |